Dear Colleagues,

This month, our clinical considerations include articles on the role of the microbe in acne, data around a topical agent to treat tinea pedis, and insights on sebum interacts with airborne pollution.

Traditional approaches to treating acne are largely aimed at killing P. acnes with topical agents and oral antibiotics. This article suggests that perhaps our goal to kill P. acnes is misguided.  As our understanding of the microbial environment within the hair follicle and the role of the skin microbiota advances, perhaps the treatment of acne will involve balancing microbes versus killing P. acnes.  Learn more about this developing concept in Dr. Li’s article.

Phase 2 data shows a novel topical agen tholds promise for the treatment of tinea pedis. Nitric oxide topical gel showed safety and efficacy against T. Rubrum. This novel agent targets a new pathway to combat the common condition. Additional studies will be needed to bring this agent to market. In this article, Dr. Kircik describes the mechanism of action of nitric oxide.

Have you ever considered the effect of environmental pollutants on the health of your skin? Do your patients ask you about the effect of airborne pollutants? Dr. Draelos explains that the nanoparticles released in airborne pollution can damage to the skin via oxygen radicals. Endogenous sebum may have a protective effect, yet similar protection maybe achieved through sunscreen, moisturizers, or foundation.


Joe Gorelick, MSN, FNP-C, Dermatology Education Foundation Founder and Chairman